
Breathing New Life: The Impact of Sleeve Gastrectomy on Pulmonary Function Through Spirometry Analysis
Mohammad Hossein Maumi 1 ℗, Mohammad Samet 2 ©, Seyed Mohammad Kazem Mousavi Anari 1, Mohammad Javad Mohammadfard 1, Abolfazl Taghinejad 1
Abstract
Introduction: Obesity is a known contributor to impaired respiratory function. Sleeve gastrectomy, a common bariatric procedure, is associated with significant weight loss, potentially improving lung mechanics. This study aimed to evaluate the effects of sleeve surgery on spirometry parameters in obese patients by comparing pre- and post-operative pulmonary function tests. Methods and Materials: In this prospective observational study, 40 obese patients (14 males, 26 females) undergoing sleeve gastrectomy were evaluated. Spirometry was performed before surgery and after achieving approximately 20% weight loss. Parameters analyzed included FEV1 (liters and %), FVC (liters and %), FEV1/FVC ratio, FEF25–75% (liters and %), along with STOP-BANG and ESS scores for sleep apnea risk and daytime sleepiness, respectively. Paired t-tests were used to compare pre- and post-operative values, and gender-based subgroup analyses were conducted. Results: Post-surgery spirometry values showed statistically significant improvements across all major indices: FEV1 increased from 2.63 ± 0.59 to 2.72 ± 0.56 L (p 0.001), FEV1% rose from 98.78% to 102.63% (p 0.001), FVC improved from 2.99 ± 0.73 to 3.06 ± 0.73 L (p 0.001), FVC% increased from 95.53% to 98.53% (p 0.001), FEV1/FVC ratio improved from 87.98% to 89.34% (p 0.001), FEF25–75% rose from 3.39 ± 0.92 to 3.46 ± 0.92 L (p = 0.001), FEF25–75% % increased from 96.2% to 98.4% (p = 0.002). Additionally, the STOP-BANG and ESS scores significantly decreased post-operatively (p 0.001), indicating reduced sleep apnea risk and improved sleep quality. Subgroup analysis showed that both males and females benefited, though some spirometry parameters improved more notably in females. Conclusion and Discussion: Sleeve gastrectomy results in significant improvement in pulmonary function among obese patients, as evidenced by enhancements in all spirometry measures. These improvements may contribute to better respiratory health and reduced sleep-disordered breathing. Spirometry may be a valuable adjunct in assessing the physiological benefits of bariatric surgery beyond weight reduction.
Keywords: Gastroplasty, spirometry, Sleep Disorder , Obstructive Sleep Apnea