G-3733

Relationship Between Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio With Prognosis in Patients With Acute Ischemic Stroke in the Emergency Department of Isfahan Shariati Hospital in 2022

 Mahtab Jamali ¹, Maryam Sarrami ¹ ℗, Seyed Ali Mirbod ² ©, Elina Aslemolapour ¹   

 
Abstract

Introduction: Stroke is an emerging public health concern and remains one of the leading causes of mortality and disability worldwide, influenced by multiple factors. Specifically, high levels of the Neutrophil-to-Lymphocyte Ratio (NLR) have previously been associated with the severity of stroke, poor functional outcomes, and recurrent ischemic events in stroke patients. Recently, the Platelet-to-Lymphocyte Ratio (PLR) has also been reported as a potential biomarker in various conditions, including Acute Ischemic Stroke (AIS), carotid artery stenosis, and post-stroke depression. Materials and Method: This study is a descriptive-analytical cross-sectional study conducted on 163 patients with acute ischemic stroke admitted to Isfahan Shariati Hospital. This study aimed to examine the relationship between NLR and PLR with the prognosis of patients with acute ischemic stroke in the emergency department of Isfahan Shariati Hospital in 2022. After data collection, the analyses were performed using SPSS version 26. Results: In this study, the mean age of patients was 68.85 years (with a standard deviation of 13.46). The mean lymphocyte count was 24.68 (SD: 13.74), the mean neutrophil count was 65.24 (SD: 15.911), the mean platelet count was 211.94 (SD: 83.82), the mean NLR was 4.55 (SD: 16.77), and the mean PLR was 13.47 (SD: 16.46). Additionally, NLR showed a statistically significant effect on the prognosis of acute ischemic stroke; as NLR increased, the prognosis worsened. PLR showed astatistically significant effect on the prognosis of acute ischemic stroke; as PLR increased,the prognosis worsened Conclusion: Based on the findings of this study, NLR significantly affects the poor prognosis of patients with acute ischemic stroke, and this information may be useful for healthcare providers and specialists.

Keywords: Platelet, Lymphocyte, Neutrophil, Acute Ischemic Stroke