
A nanostructured copper-cobalt mixed oxide composite designed for enzyme-free glucose detection
Fatemeh Bagheri 1 ℗, Seyyed Ebrahim Mousavifard 2 ©, Mahsa Keshavarz 3
Abstract
Diabetes mellitus, a prevalent chronic condition, poses significant challenges to global health, as recognized by the World Health Organization. Effective management of diabetes necessitates regular monitoring of blood glucose levels to maintain them within a physiological range. This study aimed to develop a novel non-enzymatic glucose sensor utilizing hollow, nanoporous copper cobaltite spheres for accurate glucose quantification. Current commercial glucose sensors predominantly rely on enzymatic electrochemical systems, typically employing glucose oxidase. However, these enzymatic sensors exhibit limitations, including sensitivity to pH fluctuations,reduced stability under varying temperature and humidity conditions, high costs, and complex enzyme immobilization processes. Consequently, there is a growing emphasis on developing fourth-generation, enzyme-free glucose sensors to overcome these challenges.
Keywords: Non-enzymatic sensor, glucose detection, nanostructured materials, copper cobalt mixed oxide